Tanespimycin Production
Tanespimycin Production Costs Report | Issue A | Q2 2024
Report Details |
0.10 kta United States-based plant | Q2 2024 | 107 pages |
This report presents a cost analysis of a 0.10 kta (kilo metric ton per annum) United States-based plant. You can add a customized cost analysis, assuming another location (country), when ordering a premium edition of this report.
Report Abstract
This report presents the economics of the production of Tanespimycin production from corn in the United States, via a typical fermentation process. Initially, corn starch is converted to glucose by alpha amylase. The glucose generated is then fermented to geldanamycin. Finally, geldanamycin is converted to Tanespimycin.
The report provides a comprehensive study of Tanespimycin production and related Tanespimycin production cost, covering three key aspects: a complete description of the Tanespimycin production process examined; an in-depth analysis of the related Tanespimycin plant capital cost (Capex); and an evaluation of the respective Tanespimycin plant operating costs (Opex).
The Tanespimycin production process description includes a block flow diagram (BFD), an overview of the industrial site installations, detailing both the process unit and the necessary infrastructure, process consumption figures and comprehensive process flow diagrams (PFD). The Tanespimycin plant capital cost analysis breaks down the Capex by plant cost (i.e., ISBL, OSBL and Contingency); owner's cost; working capital; and costs incurred during industrial plant commissioning and start-up. The Tanespimycin plant operating costs analysis covers operating expenses, including variable costs like raw materials and utilities, and fixed costs such as maintenance, labor, and depreciation.
Process Overview
Product
Tanespimycin. Tanespimycin is a water-soluble benzoquinone antineoplastic antibiotic. It acts as an inhibitor of Hsp90, a heat shock protein that plays a central role in promoting the functionality and stability of a group of proteins associated with cancer. Tanespimycin is a derivative of geldanamycin, an antibiotic that is being studied in the treatment of cancer and patients with certain types of leukemia or solid tumors, especially kidney tumors.
Raw Material
Corn. Corn is available at relatively low and steady prices, it has high starch content, is easily stored, transported and handled. Such characteristics led naturally to the development of several processes to recover its starch and to process it into several industrial products. Most industrial processes make use of the shelled corn, which has been stripped from the cob during harvesting. The shelled corn is converted to other products through milling and refining. Corn milling processes can be divided in two main groups, wet milling and dry milling. In the wet milling, the corn kernel is milled in such a way that its components can be separated in an aqueous medium. In the dry milling the components of the kernel are separated using screening and air classification, but the fractionation is less efficient. Wet milling is generally used to produce high quality corn starch at high yields along with its by-products used in the animal feed (corn gluten meal and corn gluten feed) and food (corn oil) industries. Dry milling is widely used in the production of fuel Ethanol by fermentation of raw corn starch, other uses include the brewing and cereals industries.
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Production Process Information
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Production Costs Datasheet
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Production Process Information
Process Consumptions
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Plant Capital Cost Summary
Operating Cost Summary
Production Costs Datasheet
Plant Capital Cost Details
Operating Cost Details
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Production Process Information
Process Consumptions
Labor Requirements
Plant Capital Cost Summary
Operating Cost Summary
Production Costs Datasheet
Plant Capital Cost Details
Operating Cost Details
Plant Cost Breakdowns
Plant Capacity Assessment
Process Flow Diagrams
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Content Highlights
Plant Capital Cost Summary
Summary outlining the capital cost required for building the Tanespimycin production plant examined
Plant Capital Cost Details
Detailing of fixed capital (ISBL, OSBL & Owner’s Cost), working capital and additional capital requirements
Plant Cost Breakdowns
Breakdown of Tanespimycin process unit (ISBL) costs and infrastructure (OSBL) costs; plant cost breakdown per discipline
Operating Costs Summary
Summary presenting the operating variable costs and the total operating cost of the Tanespimycin production plant studied
Operating Cost Details
Detailing of utilities costs, operating fixed costs and depreciation
Plant Capacity Assessment
Comparative analysis of capital investment and operating costs for different Tanespimycin plant capacities
Production Process Information
Block Flow Diagram, descriptions of process unit (ISBL) and site infrastructure (OSBL)
Process Consumptions
Raw materials and utilities consumption figures, by-products credits, labor requirements
Process Diagrams
Process flow diagrams (PFD), equipment list and industrial site configuration
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