Production Cost Report
ICC - Is Bespoken: 0
ICC - Main References: ?
ICC - Issue: A
ICC - Volume: 304
ICC - Report ID: 304-A
ICC - Report Location: United States
ICC - Is Popular: 0
ICC - Is Developed: 0
ICC - Title: Tanespimycin Production
ICC - Show Overview: 1
ICC - Report Location ID: 1
ICC - Plant Capacity Unit ID: 14
ICC - Related Reports List: 241-C,202-D
ICC - Report Location Code: USA
ICC - Delivery Times: {"versions":{"1":{"1":{"time":"11","price":0},"2":{"time":"6","price":"699"}},"2":{"1":{"time":"11","price":0},"2":{"time":"6","price":"699"}},"3":{"1":{"time":"13","price":0},"2":{"time":"8","price":"699"}}},"unit":"d"}
ICC - Prices: {"versions":{"1":{"1":"1999","2":"1999","3":"1999"},"2":{"1":"2999","2":"2999","3":"2999"},"3":{"1":"4799","2":"4799","3":"4799"}},"currency":"USD"}
ICC - Plant Capacity Unit Name: kilo metric ton per annum
ICC - Plant Capacity Unit Short Name: kta
ICC - Process Overview Image: //cdn.intratec.us/images/icc/process-overview/304-A.jpg
ICC - Process Overview Text: <h6>Product</h6> <p><b>Tanespimycin</b>. Tanespimycin is a water-soluble benzoquinone antineoplastic antibiotic. It acts as an inhibitor of Hsp90, a heat shock protein that plays a central role in promoting the functionality and stability of a group of proteins associated with cancer. Tanespimycin is a derivative of geldanamycin, an antibiotic that is being studied in the treatment of cancer and patients with certain types of leukemia or solid tumors, especially kidney tumors.</p> <h6>Raw Material</h6> <p><b>Corn</b>. Corn is available at relatively low and steady prices, it has high starch content, is easily stored, transported and handled. Such characteristics led naturally to the development of several processes to recover its starch and to process it into several industrial products. Most industrial processes make use of the shelled corn, which has been stripped from the cob during harvesting. The shelled corn is converted to other products through milling and refining. Corn milling processes can be divided in two main groups, wet milling and dry milling. In the wet milling, the corn kernel is milled in such a way that its components can be separated in an aqueous medium. In the dry milling the components of the kernel are separated using screening and air classification, but the fractionation is less efficient. Wet milling is generally used to produce high quality corn starch at high yields along with its by-products used in the animal feed (corn gluten meal and corn gluten feed) and food (corn oil) industries. Dry milling is widely used in the production of fuel Ethanol by fermentation of raw corn starch, other uses include the brewing and cereals industries.</p>
ICC - Process Schematic Image: //cdn.intratec.us/images/icc/process-schematics/304-A.jpg
ICC - Short Description: This report presents the economics of the production of Tanespimycin production from corn in the United States, via a typical fermentation process. Initially, corn starch is converted to glucose by alpha amylase. The glucose generated is then fermented to geldanamycin. Finally, geldanamycin is converted to Tanespimycin.
ICC - Main Product: Tanespimycin
ICC - Plant Capacity: 0.10
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ICC - Table Count: {"versions":{"1":"22","2":"28","3":"34"}}

Tanespimycin Production

Tanespimycin Production Costs Report | Issue A | Q2 2024

Production Cost Report

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0.10 kta United States-based plant   |   Q2 2024   |   107 pages

This report presents a cost analysis of a 0.10 kta (kilo metric ton per annum) United States-based plant. You can add a customized cost analysis, assuming another location (country), when ordering a premium edition of this report.

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Production Process Information

Process Consumptions

Labor Requirements

Plant Capital Cost Summary

Operating Cost Summary

Production Costs Datasheet

Plant Capital Cost Details

Operating Cost Details

Plant Cost Breakdowns

Plant Capacity Assessment

Process Flow Diagrams

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Content Highlights

Plant Capital Cost Summary

Summary outlining the capital cost required for building the Tanespimycin production plant examined

Plant Capital Cost Details

Detailing of fixed capital (ISBL, OSBL & Owner’s Cost), working capital and additional capital requirements

Plant Cost Breakdowns

Breakdown of Tanespimycin process unit (ISBL) costs and infrastructure (OSBL) costs; plant cost breakdown per discipline

Operating Costs Summary

Summary presenting the operating variable costs and the total operating cost of the Tanespimycin production plant studied

Operating Cost Details

Detailing of utilities costs, operating fixed costs and depreciation

Plant Capacity Assessment

Comparative analysis of capital investment and operating costs for different Tanespimycin plant capacities

Production Process Information

Block Flow Diagram, descriptions of process unit (ISBL) and site infrastructure (OSBL)

Process Consumptions

Raw materials and utilities consumption figures, by-products credits, labor requirements

Process Diagrams

Process flow diagrams (PFD), equipment list and industrial site configuration

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Other Related Production Cost Reports

Polylactic Acid Production from Corn

This study approaches the economics of Polylactic Acid production from corn in the United States. Initially, shelled corn is passed through a wet milling process to form corn starch, which is hydrolyzed to dextrose. Then, dextrose is fermented into lactic acid in a process similar to Cargill process. Finally, lactic acid is polymerized using a melt-phase polymerization process similar to the one proposed by NatureWorks.

Details: 140 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue D   From $1,499 USD

The cost analyses presented in this report target a 140 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Ethanol Production from Corn Dry Milling

This study presents the economics of hydrous Ethanol production from corn in the United States using a typical dry milling process. Initially, corn is ground, slurried with water and then submitted to enzymatic hydrolysis, which convert starch to glucose. Next, the glucose is fermented to Ethanol by yeasts, yielding Hydrous Ethanol.

Details: 300 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue C   From $799 USD

The cost analyses presented in this report target a 300 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

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