Production Cost Report
ICC - Is Bespoken: 0
ICC - Main References: ?
ICC - Issue: A
ICC - Volume: 306
ICC - Report ID: 306-A
ICC - Report Location: United States
ICC - Is Popular: 0
ICC - Is Developed: 1
ICC - Title: Feed-Grade Riboflavin Production
ICC - Show Overview: 1
ICC - Report Location ID: 1
ICC - Plant Capacity Unit ID: 14
ICC - Volume Reports List: 306-B
ICC - Related Reports List: 370-A
ICC - Report Location Code: USA
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ICC - Prices: {"versions":{"1":{"1":"1999","2":"1999","3":"1999"},"2":{"1":"2999","2":"2999","3":"2999"},"3":{"1":"4799","2":"4799","3":"4799"}},"currency":"USD"}
ICC - Plant Capacity Unit Name: kilo metric ton per annum
ICC - Plant Capacity Unit Short Name: kta
ICC - Process Overview Image: //cdn.intratec.us/images/icc/process-overview/306-A.jpg
ICC - Process Overview Text: <h6>Product</h6> <b>Riboflavin</b></p></b></p> <h6>Raw Materials</h6> <p><b>Chemicals</b></p>, <p><b>Glucose Syrup</b></p>, <p><b>Corn Steep Liquor</b></p>, <p><b>Yeast Extract</b></p>
ICC - Process Schematic Image: //cdn.intratec.us/images/icc/process-schematics/306-A.jpg
ICC - Process Schematic Text: <p>The process under analysis comprises two major sections: (1) Fermentation; and (2) Product Recovery and Purification.</p><p>Fermentation. Initially, the culture media used in the pre-fermentation and in the fed-batch fermentation are prepared by diluting the nutrients in water. The applied recombinant microorganism is propagated in an aerobic pre-fermentation step to obtain the proper inoculum concentration. When there is a sufficient mass of bacteria colony, the microorganism inoculum from the pre-fermentation step is fed into the fermenters. Fed-batch medium is continuously supplied to the fermenters, and the main fermentation is also carried out under aerobic process conditions. The pH control is made by addition of a solution of ammonia (NH3) and sulfuric acid, so as to keep the pH of the fermentation broth around 7. The fermentation is allowed to proceed for 48 hours, when the feeding is suspended and the fermentation is interrupted.</p><p>Product Recovery and Purification. The fermentation broth obtained in each main fermenter at the end of the fed-batch phase is fed to an agitated, jacketed tank where it is heated at about 60 °C for approximately 30 minutes for pasteurization. The pasteurized broth, rich in Riboflavin, is then fed to three decanter centrifuges operating in series for the recovery of a product with a purity of about 90 wt%. After each centrifugation step, the separated denser layer (richer in Riboflavin than in the previous step) is re-dissolved and forwarded to a subsequent centrifuge. The Riboflavin cake is treated with hot hydrochloric acid for further degradation of cells and cell constituents. The treated suspension is cooled and subsequently directed to a vacuum belt filter, where Riboflavin is separated and washed. The wet Riboflavin cake is conveyed to a rotary dryer where remaining water is removed from the Riboflavin and the dried product obtained, with a purity of 96 wt%, is finally packed.</p>
ICC - Short Description: This report presents the economics of feed-grade Riboflavin production via a typical direct fermentation process using glucose as carbon source in the United States. In the process examined, Riboflavin is produced by fermentation of a glucose syrup. After fermentation, the broth is pasteurized for the inactivation of the microorganisms, Riboflavin is recovered by centrifugation, subjected to a mineral acid treatment, dried and packed. The final product obtained is 96 wt% Riboflavin (feed-grade).
ICC - Main Product: Riboflavin
ICC - Plant Capacity: 1.00
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Feed-Grade Riboflavin Production

Riboflavin Production Costs Report | Issue A | Q3 2024

Production Cost Report

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1 kta United States-based plant   |   Q3 2024   |   107 pages

This report presents a cost analysis of a 1 kta (kilo metric ton per annum) United States-based plant. You can add a customized cost analysis, assuming another location (country), when ordering a premium edition of this report.

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Production Process Information

Process Consumptions

Labor Requirements

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Production Costs Datasheet

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Production Process Information

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Production Process Information

Process Consumptions

Labor Requirements

Plant Capital Cost Summary

Operating Cost Summary

Production Costs Datasheet

Plant Capital Cost Details

Operating Cost Details

Plant Cost Breakdowns

Plant Capacity Assessment

Process Flow Diagrams

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Content Highlights

Plant Capital Cost Summary

Summary outlining the capital cost required for building the Riboflavin production plant examined

Plant Capital Cost Details

Detailing of fixed capital (ISBL, OSBL & Owner’s Cost), working capital and additional capital requirements

Plant Cost Breakdowns

Breakdown of Riboflavin process unit (ISBL) costs and infrastructure (OSBL) costs; plant cost breakdown per discipline

Operating Costs Summary

Summary presenting the operating variable costs and the total operating cost of the Riboflavin production plant studied

Operating Cost Details

Detailing of utilities costs, operating fixed costs and depreciation

Plant Capacity Assessment

Comparative analysis of capital investment and operating costs for different Riboflavin plant capacities

Production Process Information

Block Flow Diagram, descriptions of process unit (ISBL) and site infrastructure (OSBL)

Process Consumptions

Raw materials and utilities consumption figures, by-products credits, labor requirements

Process Diagrams

Process flow diagrams (PFD), equipment list and industrial site configuration

Other Riboflavin Production Cost Reports

Food-Grade Riboflavin Production

This report presents a cost analysis of food-grade Riboflavin production via a typical direct fermentation process using glucose as carbon source in the USA. In the process examined, Riboflavin is produced by fermentation of a glucose syrup. After fermentation, the broth is pasteurized for the inactivation of the microorganisms, Riboflavin is recovered by centrifugation, subjected to a mineral acid treatment, re-crystallized for further purification, dried and packed. The final product obtained is 99 wt% Riboflavin (food-grade).

Details: 2 kta United States-based plant   |   Q3 2024   |   107 pages   |   Issue B   From $1,999 USD

The cost analyses presented in this report target a 2 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

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Other Related Production Cost Reports

Glucose Syrup Production

This report presents the economics of Glucose Syrup production from shelled corn. In this process, shelled corn is passed through a wet milling process to recover the corn starch, which, in turn, passes through two subsequent hydrolysis steps for the generation of glucose. The economic analysis performed assumes a plant located in the United States.

Details: 40 kta United States-based plant   |   Q3 2024   |   107 pages   |   Issue A   From $799 USD

The cost analyses presented in this report target a 40 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

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