Commodity Production Costs Report

Bio-Butadiene Production from Glucose (Aerobic Fermentation)

Butadiene Operating Costs & Plant Construction Costs

165 kta United States-based plant | 107 Pages | Issue D | Q3 2024
Starting at $799 USD | See Report Editions Prices

It presents the economics of bio-based 1,3-Butadiene (BD) production from glucose syrup in the United States using a direct aerobic fermentation process similar to the one proposed by Global Bioenergies.

The report provides a comprehensive study of Butadiene production and related Butadiene production cost, covering three key aspects: a complete description of the Butadiene production process examined; an in-depth analysis of the related Butadiene plant capital cost (Capex); and an evaluation of the respective Butadiene plant operating costs (Opex).

The Butadiene production process description includes a block flow diagram (BFD), an overview of the industrial site installations, detailing both the process unit and the necessary infrastructure, process consumption figures and comprehensive process flow diagrams (PFD). The Butadiene plant capital cost analysis breaks down the Capex by plant cost (i.e., ISBL, OSBL and Contingency); owner's cost; working capital; and costs incurred during industrial plant commissioning and start-up. The Butadiene plant operating costs analysis covers operating expenses, including variable costs like raw materials and utilities, and fixed costs such as maintenance, labor, and depreciation.

Key reference(s): ?

Butadiene Production Cost Report Process Schematic

The process under analysis comprises three major sections: (1) Fermentation; (2) Fermentation broth treatment; and (3) Butadiene purification.

Fermentation. The culture media is prepared by diluting the glucose syrup and nutrients in water. A genetically re-engineered yeast is propagated in an aerobic pre-fermentation step to obtain the proper inoculum concentration. The fermentation is carried out in fed-batch mode and under aerobic process conditions, in agitated fermenters equipped with internal coil. The fermentation step generates fermenter off-gas, which comprises the crude Butadiene product, and fermentation broth.

Fermentation broth treatment. After fermentation, cell biomass is separated from the fermentation broth. The clarified broth then is submitted to an ultrafiltration step, used to remove the remaining contaminants. The resulting aqueous stream may be discarded as waste water.

Butadiene purification. Initially, off-gas is compressed and cooled. The compressed gas is fed in a absorber column, where N-dodecane solvent absorbs the Butadiene. In the next column, In the Stripper Column, Butadiene is separated from the solvent. The recovered solvent is fed into a decanter for water removal before being recycled to first column. The Butadiene-containing stream is transferred into the Adsorption System. There, The oxygenates are removed by adsorption in adequate media. The oxygenate-free crude Butadiene is further purified in a last distillation column for heavy ends impurities separation. Butadiene with purity >99.7 wt% is recovered.

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  • Production Process Information
  • Process Consumptions
  • Labor Requirements
  • Plant Capital Cost Summary
  • Operating Cost Summary
  • Production Costs Datasheet
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 80 Pages | 22 Tables | 9 Images

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Table of Contents


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  • Production Process Information
  • Process Consumptions
  • Labor Requirements
  • Plant Capital Cost Summary
  • Operating Cost Summary
  • Production Costs Datasheet
  • Plant Capital Cost Details
  • Operating Cost Details
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 90 Pages | 28 Tables | 13 Images

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Table of Contents


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  • Production Process Information
  • Process Consumptions
  • Labor Requirements
  • Plant Capital Cost Summary
  • Operating Cost Summary
  • Production Costs Datasheet
  • Plant Capital Cost Details
  • Operating Cost Details
  • Plant Cost Breakdowns
  • Plant Capacity Assessment
  • Process Flow Diagrams
  • Costs in Different Countries Add-on
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  • 107 Pages | 34 Tables | 22 Images
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Content Highlights

Plant Capital Cost Summary

Summary outlining the capital cost required for building the Butadiene production plant examined.

Plant Capital Cost Details

Detailing of fixed capital (ISBL, OSBL & Owner’s Cost), working capital and additional capital requirements.

Plant Cost Breakdowns

Breakdown of Butadiene process unit (ISBL) costs and infrastructure (OSBL) costs; plant cost breakdown per discipline.

Operating Costs Summary

Summary presenting the operating variable costs and the total operating cost of the Butadiene production plant studied.

Operating Cost Details

Detailing of utilities costs, operating fixed costs and depreciation.

Plant Capacity Assessment

Comparative analysis of capital investment and operating costs for different Butadiene plant capacities.

Production Process Information

Block Flow Diagram, descriptions of process unit (ISBL) and site infrastructure (OSBL).

Process Consumptions

Raw materials and utilities consumption figures, by-products credits, labor requirements

Process Diagrams

Process flow diagrams (PFD), equipment list and industrial site configuration

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