Commodity Production Costs Report
Bio-Butanediol Production from Glucose (Direct Fermentation)
Butanediol Operating Costs & Plant Construction Costs
This report presents the economics of bio-based 1,4-Butanediol (BDO) production from glucose syrup in a plant located in the United States. This process, similar to the one proposed by Genomatica, consists in a direct fermentation of glucose syrup, producing BDO, which is then submitted to purifying steps.
The report provides a comprehensive study of Butanediol production and related Butanediol production cost, covering three key aspects: a complete description of the Butanediol production process examined; an in-depth analysis of the related Butanediol plant capital cost (Capex); and an evaluation of the respective Butanediol plant operating costs (Opex).
The Butanediol production process description includes a block flow diagram (BFD), an overview of the industrial site installations, detailing both the process unit and the necessary infrastructure, process consumption figures and comprehensive process flow diagrams (PFD). The Butanediol plant capital cost analysis breaks down the Capex by plant cost (i.e., ISBL, OSBL and Contingency); owner's cost; working capital; and costs incurred during industrial plant commissioning and start-up. The Butanediol plant operating costs analysis covers operating expenses, including variable costs like raw materials and utilities, and fixed costs such as maintenance, labor, and depreciation.
Key reference(s): ?
The process under analysis comprises three major sections: (1) fermentation; (2) separation; and (3) purification.
* Fermentation. In the fermentation area, 1,4-Butanediol is produced by fermentation of glucose using a recombinant microorganism. The main fermentation is performed in fed-batch mode under aerobic process conditions in agitated, jacketed fermenters. The fermentation temperature is controlled by circulating cooling water through the fermenter jackets. The pH is controlled by ammonia injection.
* Separation. The resulting fermentation broth is a complex mixture of water, Butanediol, byproducts, cell bodies, residual media, residual substrate, and feedstock/media impurities, which needs to pass through a series of separation steps. Those steps include centrifugation, ultrafiltration, nanofiltration and ion exchange (targeting to remove cell debris, sugars and salts), as well as evaporation for removing water.
* Purification. The concentrated solution is fed to a distillation column for light end impurities separation and subsequently to another column, for heavy ends separation. The final product, obtained from the second column is high-purity 99.5 wt.% BDO.
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Professional report based on Q3 2024 economic data, ensuring timely evaluations.
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Content Highlights
Plant Capital Cost Summary
Summary outlining the capital cost required for building the Butanediol production plant examined.
Plant Capital Cost Details
Detailing of fixed capital (ISBL, OSBL & Owner’s Cost), working capital and additional capital requirements.
Plant Cost Breakdowns
Breakdown of Butanediol process unit (ISBL) costs and infrastructure (OSBL) costs; plant cost breakdown per discipline.
Operating Costs Summary
Summary presenting the operating variable costs and the total operating cost of the Butanediol production plant studied.
Operating Cost Details
Detailing of utilities costs, operating fixed costs and depreciation.
Plant Capacity Assessment
Comparative analysis of capital investment and operating costs for different Butanediol plant capacities.
Production Process Information
Block Flow Diagram, descriptions of process unit (ISBL) and site infrastructure (OSBL).
Process Consumptions
Raw materials and utilities consumption figures, by-products credits, labor requirements
Process Diagrams
Process flow diagrams (PFD), equipment list and industrial site configuration
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Other Butanediol Production Cost Reports
Bio-Butanediol from Glucose (Succinic Acid as Intermediate)
This report examines the costs related to Butanediol production from glucose syrup. Initially, glucose is fermented to produce succinic acid, which is then hydrogenated to produce butanediol. The economic analysis is based on a plant constructed in the United States.
Details: 50 kta United States-based plant | Q3 2024 | 107 pages | Issue B | From $1,199 USD
Butanediol Production from Succinic Acid
This feasibility study examines 1,4-Butanediol (BDO) production from succinic acid in the United States using a hydrogenation process similar to the one proposed by BioAmber.
Details: 60 kta United States-based plant | Q3 2024 | 107 pages | Issue C | From $799 USD
Butanediol Production from Acetylene
This report presents the economics of an 1,4-Butanediol (BDO) production process from acetylene and formaldehyde in the United States. In this process, acetylene initially reacts with formaldehyde by addition, forming 1,4-butynediol. The butynediol is then hydrogenated to produce BDO. It is a typical acetylene-based Reppe process.
Details: 120 kta United States-based plant | Q3 2024 | 107 pages | Issue D | From $799 USD
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Other Related Production Cost Reports
Tetrahydrofuran Production
It presents the economics of Tetrahydrofuran (THF) production from butanediol (BDO) in the United States, using a dehydration process similar to Davy Process Technology (DPT). The BDO is very readily cyclized to THF with elimination of water by acid catalysis.
Details: 60 kta United States-based plant | Q3 2024 | 107 pages | Issue A | From $799 USD
Glucose Syrup Production
This report presents the economics of Glucose Syrup production from shelled corn. In this process, shelled corn is passed through a wet milling process to recover the corn starch, which, in turn, passes through two subsequent hydrolysis steps for the generation of glucose. The economic analysis performed assumes a plant located in the United States.
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