Production Cost Report
ICC - Is Bespoken: 0
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ICC - Issue: A
ICC - Volume: 27
ICC - Report ID: 027-A
ICC - Report Location: United States
ICC - Is Popular: 0
ICC - Is Developed: 1
ICC - Title: Bio-Butanediol Production from Glucose (Direct Fermentation)
ICC - Show Overview: 1
ICC - Report Location ID: 1
ICC - Plant Capacity Unit ID: 14
ICC - Volume Reports List: 027-A,027-B,027-C,027-D,027-E,027-F,027-G,027-H,027-I,027-J,027-K,027-L
ICC - Related Reports List: 370-A,177-A
ICC - Report Location Code: USA
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ICC - Plant Capacity Unit Name: kilo metric ton per annum
ICC - Plant Capacity Unit Short Name: kta
ICC - Process Overview Image: //cdn.intratec.us/images/icc/process-overview/027-A.jpg
ICC - Process Overview Text: <h6>Product</h6> <p><b>Butanediol</b>. Butanediol is a versatile organic chemical used as an intermediate in the production of a wide range of industrial and consumer products. It plays a crucial role in manufacturing polyurethanes, engineering plastics, and fibers, and is also used in the synthesis of pharmaceuticals, solvents, and coatings. Butanediol is typically produced through the hydrogenation of maleic anhydride or succinic acid. It is handled and stored as a stable liquid at room temperature, and its demand continues to grow in sectors such as automotive, construction, and electronics.</p> <h6>Raw Materials</h6> <p><b>Chemicals</b>. </p> <b>Glucose Syrup</b>. Glucose (C6H12O6), also known as D-glucose and dextrose, is the most abundant sugar in nature. Commercial glucose products are available in both dry and syrup forms in a variety of purities and concentrations. Glucose uses include pharmaceuticals, food, chemicals and fuels. This compound is used as raw material in fermentative processes for the production of vitamins, organic acids, antibiotics, amino acids, enzymes, and polysaccharides.</p> <b>Ammonia</b>. Ammonia (NH3) is one of the most produced synthetic chemicals worldwide. The main application of this world class commodity is in nitrogen fertilizers, followed by the synthesis of nitric acid. It is also used, to a lesser extent, in several other applications such as pulping of wood and as ingredient in household cleaners and drugs. Ammonia produced basically by the reaction between nitrogen and hydrogen, in a 1:3 stoichiometric ratio. Its production routes are related to the source of the hydrogen used, being steam reforming the main one. At atmospheric pressure, it boils at - 33 °C, so it is stored in refrigerated tanks to be kept as liquid.</p>
ICC - Process Schematic Image: //cdn.intratec.us/images/icc/process-schematics/027-A.jpg
ICC - Process Schematic Text: <p>The process under analysis comprises three major sections: (1) fermentation; (2) separation; and (3) purification.</p><p>* Fermentation. In the fermentation area, 1,4-Butanediol is produced by fermentation of glucose using a recombinant microorganism. The main fermentation is performed in fed-batch mode under aerobic process conditions in agitated, jacketed fermenters. The fermentation temperature is controlled by circulating cooling water through the fermenter jackets. The pH is controlled by ammonia injection.</p><p>* Separation. The resulting fermentation broth is a complex mixture of water, Butanediol, byproducts, cell bodies, residual media, residual substrate, and feedstock/media impurities, which needs to pass through a series of separation steps. Those steps include centrifugation, ultrafiltration, nanofiltration and ion exchange (targeting to remove cell debris, sugars and salts), as well as evaporation for removing water.</p><p>* Purification. The concentrated solution is fed to a distillation column for light end impurities separation and subsequently to another column, for heavy ends separation. The final product, obtained from the second column is high-purity 99.5 wt.% BDO.</p>
ICC - Short Description: This report presents the economics of bio-based 1,4-Butanediol (BDO) production from glucose syrup in a plant located in the United States. This process, similar to the one proposed by Genomatica, consists in a direct fermentation of glucose syrup, producing BDO, which is then submitted to purifying steps.
ICC - Main Product: Butanediol
ICC - Plant Capacity: 75.00
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Bio-Butanediol Production from Glucose (Direct Fermentation)

Butanediol Production Costs Report | Issue A | Q2 2024

Production Cost Report

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75 kta United States-based plant   |   Q2 2024   |   107 pages   |   Delivered in PDF

This report presents a cost analysis of a 75 kta (kilo metric ton per annum) United States-based plant. You can add a customized cost analysis, assuming another location (country), when ordering a premium edition of this report.

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Production Process Information

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Production Process Information

Process Consumptions

Labor Requirements

Plant Capital Cost Summary

Operating Cost Summary

Production Costs Datasheet

Plant Capital Cost Details

Operating Cost Details

Plant Cost Breakdowns

Plant Capacity Assessment

Process Flow Diagrams

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Content Highlights

Plant Capital Cost Summary

Summary outlining the capital cost required for building the Butanediol production plant examined

Plant Capital Cost Details

Detailing of fixed capital (ISBL, OSBL & Owner’s Cost), working capital and additional capital requirements

Plant Cost Breakdowns

Breakdown of Butanediol process unit (ISBL) costs and infrastructure (OSBL) costs; plant cost breakdown per discipline

Operating Costs Summary

Summary presenting the operating variable costs and the total operating cost of the Butanediol production plant studied

Operating Cost Details

Detailing of utilities costs, operating fixed costs and depreciation

Plant Capacity Assessment

Comparative analysis of capital investment and operating costs for different Butanediol plant capacities

Production Process Information

Block Flow Diagram, descriptions of process unit (ISBL) and site infrastructure (OSBL)

Process Consumptions

Raw materials and utilities consumption figures, by-products credits, labor requirements

Process Diagrams

Process flow diagrams (PFD), equipment list and industrial site configuration

Other Butanediol Production Cost Reports

Bio-Butanediol Production from Glucose (Direct Fermentation)

This report presents the economics of bio-based 1,4-Butanediol (BDO) production from glucose syrup in a plant located in the United States. This process, similar to the one proposed by Genomatica, consists in a direct fermentation of glucose syrup, producing BDO, which is then submitted to purifying steps.

Details: 75 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue A   From $799 USD

The cost analyses presented in this report target a 75 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Bio-Butanediol from Glucose (Succinic Acid as Intermediate)

This report examines the costs related to Butanediol production from glucose syrup. Initially, glucose is fermented to produce succinic acid, which is then hydrogenated to produce butanediol. The economic analysis is based on a plant constructed in the United States.

Details: 50 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue B   From $1,199 USD

The cost analyses presented in this report target a 50 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Butanediol Production from Succinic Acid

This feasibility study examines 1,4-Butanediol (BDO) production from succinic acid in the United States using a hydrogenation process similar to the one proposed by BioAmber.

Details: 60 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue C   From $799 USD

The cost analyses presented in this report target a 60 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Butanediol Production from Acetylene

This report presents the economics of an 1,4-Butanediol (BDO) production process from acetylene and formaldehyde in the United States. In this process, acetylene initially reacts with formaldehyde by addition, forming 1,4-butynediol. The butynediol is then hydrogenated to produce BDO. It is a typical acetylene-based Reppe process.

Details: 120 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue D   From $799 USD

The cost analyses presented in this report target a 120 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Butanediol Production from Maleic Anhydride

This report presents an economic analysis of 1,4-Butanediol (BDO) production from maleic anhydride in the United States using a process similar to the one proposed by JM Davy. Initially, maleic anhydride is reacted with methanol to produce dimethyl maleate (DMM). The DMM is then hydrogenated to BDO.

Details: 75 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue E   From $799 USD

The cost analyses presented in this report target a 75 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Butanediol Production from Propylene

This feasibility analysis is about 1,4-Butanediol (BDO) production from propylene in the United States using an allyl alcohol process. Initially, propylene is reacted with acetic acid and oxygen, producing allyl acetate. The allyl acetate is then hydrolyzed, yielding allyl alcohol. Finally, the allyl alcohol is converted by hydroformylation and hydrogenation to BDO.

Details: 65 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue F   From $1,199 USD

The cost analyses presented in this report target a 65 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Butanediol Production from Propylene Oxide

This report shows a techno-economic analysis related to the construction of a plant in the United States for 1,4-Butanediol (BDO) production from propylene oxide using a process similar to LyondellBasell. Initially, propylene oxide is isomerized to allyl alcohol. The allyl alcohol then reacts with syngas, generating 4-hydroxybutyraldehyde, which is finally hydrogenated to BDO.

Details: 100 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue G   From $799 USD

The cost analyses presented in this report target a 100 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Butanediol Production from Butadiene

This assessment examines a technology similar to the process proposed by Mitsubishi Chemical for 1,4-Butanediol (BDO) production from butadiene (BD) in the United States. In this process, BDO is produced from BD via acetoxylation.

Details: 65 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue H   From $799 USD

The cost analyses presented in this report target a 65 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Bio-Butanediol from Glucose (By-Products: THF & Ammonium Sulfate)

This report concerns the bio-based BDO production in the United States from glucose. In this report, BDO is produced using a two-step process similar to Myriant/JM Davy technology. In this process, glucose is fermented to succinic acid, which is then hydrogenated to BDO. Ammonium sulfate and tetrahydrofuran (THF) are generated as by-products.

Details: 65 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue I   From $1,199 USD

The cost analyses presented in this report target a 65 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Butanediol from Raw Sugar (By-Products: THF & Ammonium Sulfate)

This report concerns the bio-based BDO production in the Germany from raw sugar. In this report, BDO is produced using a two-step process similar to Myriant/JM Davy technology. In this process, raw sugar is hydrolyzed into glucose and fructose (invert sugars). The invert sugars are fermented to produce to succinic acid, that is then hydrogenated to BDO. Ammonium sulfate and tetrahydrofuran (THF) are generated as by-products.

Details: 65 kta Germany-based plant   |   Q2 2024   |   107 pages   |   Issue J   From $1,199 USD

The cost analyses presented in this report target a 65 kta (kilo metric ton per annum per annum) Germany-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Bio-Butanediol Production from Raw Sugar (Direct Fermentation)

It examines bio-based BDO production using a fermentation process similar to the one proposed by Genomatica. This report presents an economic analysis for a plant constructed in Germany using raw sugar as feedstock in the fermentation.

Details: 75 kta Germany-based plant   |   Q2 2024   |   107 pages   |   Issue K   From $799 USD

The cost analyses presented in this report target a 75 kta (kilo metric ton per annum per annum) Germany-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Bio-Butanediol from Raw Sugar (Succinic Acid as Intermediate)

This report presents the economics of bio-based 1,4-Butanediol production from raw sugar in Germany. Initially, raw sugar (sucrose) is hydrolyzed into glucose and fructose (invert sugars). The invert sugars are fermented to produce succinic acid, which is then hydrogenated to produce BDO.

Details: 50 kta Germany-based plant   |   Q2 2024   |   107 pages   |   Issue L   From $799 USD

The cost analyses presented in this report target a 50 kta (kilo metric ton per annum per annum) Germany-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

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Other Related Production Cost Reports

Tetrahydrofuran Production

It presents the economics of Tetrahydrofuran (THF) production from butanediol (BDO) in the United States, using a dehydration process similar to Davy Process Technology (DPT). The BDO is very readily cyclized to THF with elimination of water by acid catalysis.

Details: 60 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue A   From $799 USD

The cost analyses presented in this report target a 60 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Glucose Syrup Production

This report presents the economics of Glucose Syrup production from shelled corn. In this process, shelled corn is passed through a wet milling process to recover the corn starch, which, in turn, passes through two subsequent hydrolysis steps for the generation of glucose. The economic analysis performed assumes a plant located in the United States.

Details: 40 kta United States-based plant   |   Q2 2024   |   107 pages   |   Issue A   From $799 USD

The cost analyses presented in this report target a 40 kta (kilo metric ton per annum per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

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