Commodity Production Costs Report
Tanespimycin Production
Tanespimycin Operating Costs & Plant Construction Costs
This report presents the economics of the production of Tanespimycin production from corn in the United States, via a typical fermentation process. Initially, corn starch is converted to glucose by alpha amylase. The glucose generated is then fermented to geldanamycin. Finally, geldanamycin is converted to Tanespimycin.
The report provides a comprehensive study of Tanespimycin production and related Tanespimycin production cost, covering three key aspects: a complete description of the Tanespimycin production process examined; an in-depth analysis of the related Tanespimycin plant capital cost (Capex); and an evaluation of the respective Tanespimycin plant operating costs (Opex).
The Tanespimycin production process description includes a block flow diagram (BFD), an overview of the industrial site installations, detailing both the process unit and the necessary infrastructure, process consumption figures and comprehensive process flow diagrams (PFD). The Tanespimycin plant capital cost analysis breaks down the Capex by plant cost (i.e., ISBL, OSBL and Contingency); owner's cost; working capital; and costs incurred during industrial plant commissioning and start-up. The Tanespimycin plant operating costs analysis covers operating expenses, including variable costs like raw materials and utilities, and fixed costs such as maintenance, labor, and depreciation.
Key reference(s): ?
Product
Tanespimycin. Tanespimycin is a water-soluble benzoquinone antineoplastic antibiotic. It acts as an inhibitor of Hsp90, a heat shock protein that plays a central role in promoting the functionality and stability of a group of proteins associated with cancer. Tanespimycin is a derivative of geldanamycin, an antibiotic that is being studied in the treatment of cancer and patients with certain types of leukemia or solid tumors, especially kidney tumors.
Raw Material
Corn. Corn is available at relatively low and steady prices, it has high starch content, is easily stored, transported and handled. Such characteristics led naturally to the development of several processes to recover its starch and to process it into several industrial products. Most industrial processes make use of the shelled corn, which has been stripped from the cob during harvesting. The shelled corn is converted to other products through milling and refining. Corn milling processes can be divided in two main groups, wet milling and dry milling. In the wet milling, the corn kernel is milled in such a way that its components can be separated in an aqueous medium. In the dry milling the components of the kernel are separated using screening and air classification, but the fractionation is less efficient. Wet milling is generally used to produce high quality corn starch at high yields along with its by-products used in the animal feed (corn gluten meal and corn gluten feed) and food (corn oil) industries. Dry milling is widely used in the production of fuel Ethanol by fermentation of raw corn starch, other uses include the brewing and cereals industries.
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Professional report based on Q3 2024 economic data, ensuring timely evaluations.
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Content Highlights
Plant Capital Cost Summary
Summary outlining the capital cost required for building the Tanespimycin production plant examined.
Plant Capital Cost Details
Detailing of fixed capital (ISBL, OSBL & Owner’s Cost), working capital and additional capital requirements.
Plant Cost Breakdowns
Breakdown of Tanespimycin process unit (ISBL) costs and infrastructure (OSBL) costs; plant cost breakdown per discipline.
Operating Costs Summary
Summary presenting the operating variable costs and the total operating cost of the Tanespimycin production plant studied.
Operating Cost Details
Detailing of utilities costs, operating fixed costs and depreciation.
Plant Capacity Assessment
Comparative analysis of capital investment and operating costs for different Tanespimycin plant capacities.
Production Process Information
Block Flow Diagram, descriptions of process unit (ISBL) and site infrastructure (OSBL).
Process Consumptions
Raw materials and utilities consumption figures, by-products credits, labor requirements
Process Diagrams
Process flow diagrams (PFD), equipment list and industrial site configuration
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