Rifampicin Production

This report presents the economics of Rifampicin production from mixed carbon sources (peanut meal, soybean flour, glucose, and starch) in the United States, via a typical fermentation process of Nocardi mediterranei. The fermentation produces rifamycin B, which is further processed in many steps until Rifampicin is obtained.

The report provides a comprehensive study of Rifampicin production and related Rifampicin production cost, covering three key aspects: a complete description of the Rifampicin production process examined; an in-depth analysis of the related Rifampicin plant capital cost (Capex); and an evaluation of the respective Rifampicin plant operating costs (Opex).

The Rifampicin production process description includes a block flow diagram (BFD), an overview of the industrial site installations, detailing both the process unit and the necessary infrastructure, process consumption figures and comprehensive process flow diagrams (PFD). The Rifampicin plant capital cost analysis breaks down the Capex by plant cost (i.e., ISBL, OSBL and Contingency); owner's cost; working capital; and costs incurred during industrial plant commissioning and start-up. The Rifampicin plant operating costs analysis covers operating expenses, including variable costs like raw materials and utilities, and fixed costs such as maintenance, labor, and depreciation.

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