Commodity Production Costs Report

Neopentyl Glycol Production

Neopentyl Glycol Operating Costs & Plant Construction Costs

60 kta United States-based plant | 107 Pages | Issue A | Q3 2024
Starting at $799 USD | See Report Editions Prices

This report presents the economics of Neopentyl Glycol production from isobutyraldehyde, formaldehyde and hydrogen, assuming a conventional industrial process, located in the United States. In this process, formaldehyde and isobutyraldehyde are reacted via aldol condensation to form hydroxypivaldehyde, which is then converted to Neopentyl Glycol via catalytic hydrogenation.

The report provides a comprehensive study of Neopentyl Glycol production and related Neopentyl Glycol production cost, covering three key aspects: a complete description of the Neopentyl Glycol production process examined; an in-depth analysis of the related Neopentyl Glycol plant capital cost (Capex); and an evaluation of the respective Neopentyl Glycol plant operating costs (Opex).

The Neopentyl Glycol production process description includes a block flow diagram (BFD), an overview of the industrial site installations, detailing both the process unit and the necessary infrastructure, process consumption figures and comprehensive process flow diagrams (PFD). The Neopentyl Glycol plant capital cost analysis breaks down the Capex by plant cost (i.e., ISBL, OSBL and Contingency); owner's cost; working capital; and costs incurred during industrial plant commissioning and start-up. The Neopentyl Glycol plant operating costs analysis covers operating expenses, including variable costs like raw materials and utilities, and fixed costs such as maintenance, labor, and depreciation.

Key reference(s): ?

Neopentyl Glycol Production Cost Report Process Schematic

The process under analysis comprises three major sections: (1) Aldol Condensation; (2) Hydrogenation; and (3) Purification.

Aldol Condensation. An aldol reactor is fed with an aqueous solution of formaldehyde, isobutyraldehyde and triethylamine. In such reactor, an aldol condensation reaction between isobutyraldehyde and formaldehyde is carried out in the presence of triethylamine catalysts. The output from the aldol condensation reactor, containing crude hydroxypivaldehyde, is submitted to extraction with octanol and distillation for the recovery of a purified hydroxypivaldehyde.

Hydrogenation. The purified hydroxypivaldehyde is fed to a loop-type reactor, along with hydrogen gas. There, a reaction between hydroxypivaldehyde and hydrogen takes place, in the presence of Raney nickel catalysts. Such hydrogenation reaction yields a mixture containing crude Neopentyl Glycol, which is then submitted to a saponification step. In the saponification, the hydrogenation product is mixed with caustic soda, in such a way that the precursors still present in the stream are converted to Neopentyl Glycol.

Purification. In this section, the stream rich in Neopentyl Glycol and a stream containing residual NPG content are fed to an extractor. Water is used as solvent for Neopentyl Glycol removal. The aqueous phase from the extraction is fed to a distillation column, which further separates a mixture of Neopentyl Glycol and water from salt impurities. The Neopentyl Glycol and water mixture is fed to the last column, which further purifies the NPG. High-purity Neopentyl Glycol withdrawn from column bottom is routed to a finishing step and stored.

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  • Production Process Information
  • Process Consumptions
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  • Plant Capital Cost Summary
  • Operating Cost Summary
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 80 Pages | 22 Tables | 9 Images

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Table of Contents


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  • Process Consumptions
  • Labor Requirements
  • Plant Capital Cost Summary
  • Operating Cost Summary
  • Production Costs Datasheet
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  • Operating Cost Details
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 90 Pages | 28 Tables | 13 Images

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Table of Contents


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  • Production Process Information
  • Process Consumptions
  • Labor Requirements
  • Plant Capital Cost Summary
  • Operating Cost Summary
  • Production Costs Datasheet
  • Plant Capital Cost Details
  • Operating Cost Details
  • Plant Cost Breakdowns
  • Plant Capacity Assessment
  • Process Flow Diagrams
  • Costs in Different Countries Add-on
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  • 107 Pages | 34 Tables | 22 Images
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Content Highlights

Plant Capital Cost Summary

Summary outlining the capital cost required for building the Neopentyl Glycol production plant examined.

Plant Capital Cost Details

Detailing of fixed capital (ISBL, OSBL & Owner’s Cost), working capital and additional capital requirements.

Plant Cost Breakdowns

Breakdown of Neopentyl Glycol process unit (ISBL) costs and infrastructure (OSBL) costs; plant cost breakdown per discipline.

Operating Costs Summary

Summary presenting the operating variable costs and the total operating cost of the Neopentyl Glycol production plant studied.

Operating Cost Details

Detailing of utilities costs, operating fixed costs and depreciation.

Plant Capacity Assessment

Comparative analysis of capital investment and operating costs for different Neopentyl Glycol plant capacities.

Production Process Information

Block Flow Diagram, descriptions of process unit (ISBL) and site infrastructure (OSBL).

Process Consumptions

Raw materials and utilities consumption figures, by-products credits, labor requirements

Process Diagrams

Process flow diagrams (PFD), equipment list and industrial site configuration

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