Commodity Production Costs Report
Methionine Hydroxy Analog from Acrolein, Methyl Mercaptan and HCN
Methionine Operating Costs & Plant Construction Costs
This study presents the economics of Methionine Hydroxy Analog production from acrolein, methyl mercaptan, and hydrogen cyanide (HCN) in the United States. In this process, acrolein and methyl mercaptan are reacted to form methional. The methional reacts with HCN to produce hydroxy methylthiobutyronitrile (HMBN) intermediate, which is hydrolyzed to Methionine Hydroxy Analog.
The report provides a comprehensive study of Methionine production and related Methionine production cost, covering three key aspects: a complete description of the Methionine production process examined; an in-depth analysis of the related Methionine plant capital cost (Capex); and an evaluation of the respective Methionine plant operating costs (Opex).
The Methionine production process description includes a block flow diagram (BFD), an overview of the industrial site installations, detailing both the process unit and the necessary infrastructure, process consumption figures and comprehensive process flow diagrams (PFD). The Methionine plant capital cost analysis breaks down the Capex by plant cost (i.e., ISBL, OSBL and Contingency); owner's cost; working capital; and costs incurred during industrial plant commissioning and start-up. The Methionine plant operating costs analysis covers operating expenses, including variable costs like raw materials and utilities, and fixed costs such as maintenance, labor, and depreciation.
Key reference(s): ?

The process under analysis comprises three major sections: (1) HMBN Synthesis; (2) MHA Synthesis; and (3) Purification.
HMBN Synthesis. Liquid MMP is continuously fed to the HMBN reactor, while gaseous hydrogen cyanide is fed through its bottom. The reaction is catalyzed by a mixture of pyridine and acetic acid. MMP is completely converted, with high selectivity to HMBN, and few heavier by-products. The effluent from this reactor is conducted to a nitrogen stripping column to remove unconverted hydrogen cyanide, the HCN free stream is then directed to the MHA synthesis.
MHA Synthesis. HMBN undergoes hydrolysis in three steps. At first, HMBN is introduced into a continuously stirred tank reactor (CSTR) along with process water and sulfuric acid stream. HMBN reacts with water to form an amide, 2-hydroxy-4-methylthiobutanamide, and sulfuric acid behaves as a catalyst. The effluent from this reactor and additional process water are introduced into a second CSTR, operated at higher temperature. The amide content is hydrolyzed in a reaction with water and sulfuric acid forming MHA and ammonium bisulfate. The effluent from this second reactor is fed to a plug flow reactor to guarantee complete hydrolysis of the amide formed in the first step.
Purification. MHA is extracted with methyl isobutyl ketone (MIBK). The extract, rich in MHA and solvent, is steam stripped. The water and solvent are recovered from the top product and a concentrated MHA stream is recovered from the bottom. The final product composition is corrected with process water. The raffinate from the extraction, mostly water and ammonium bisulfate, is also steam stripped. The water is recovered from the top and an aqueous solution containing ammonium bisulfate is recovered from the bottoms and disposed as waste.
Report in PDF Format
Download & Explore Anytime
Access in Various Devices
Print & Read Comfortably
Share With Co-workers
Up-to-date Report
Professional report based on Q3 2024 economic data, ensuring timely evaluations.
Multiple Use Cases
Ideal for investment screening, feasibility studies, cost estimates, and research planning.
Proven Methodology
Developed using a consistent methodology honed over a decade, ensuring reliable cost analyses.
Report Editions
Content Highlights
Plant Capital Cost Summary
Summary outlining the capital cost required for building the Methionine production plant examined.
Plant Capital Cost Details
Detailing of fixed capital (ISBL, OSBL & Owner’s Cost), working capital and additional capital requirements.
Plant Cost Breakdowns
Breakdown of Methionine process unit (ISBL) costs and infrastructure (OSBL) costs; plant cost breakdown per discipline.
Operating Costs Summary
Summary presenting the operating variable costs and the total operating cost of the Methionine production plant studied.
Operating Cost Details
Detailing of utilities costs, operating fixed costs and depreciation.
Plant Capacity Assessment
Comparative analysis of capital investment and operating costs for different Methionine plant capacities.
Production Process Information
Block Flow Diagram, descriptions of process unit (ISBL) and site infrastructure (OSBL).
Process Consumptions
Raw materials and utilities consumption figures, by-products credits, labor requirements
Process Diagrams
Process flow diagrams (PFD), equipment list and industrial site configuration
Other Methionine Production Cost Reports

Bio-Methionine Production from Raw Sugar
This report presents the economics of L-Methionine production from raw sugar (sucrose) in Germany using a process similar to the technology developed by Metabolic Explorer. In this process, sucrose is diluted and sucrose is hydrolyzed into glucose and fructose (invert sugars). The invert sugars are then fermented in an aerobic environment to produce L-Methionine.
Details: 80 kta Germany-based plant | Q3 2024 | 107 pages | Issue B | From $799 USD

Bio-Methionine Production from Glucose
This report presents the economics of L-Methionine production from glucose syrup in the United States using a process similar to the technology developed by Metabolic Explorer. In this process, glucose is fermented in an aerobic environment to produce L-Methionine.
Details: 80 kta United States-based plant | Q3 2024 | 107 pages | Issue C | From $799 USD

DL-Methionine Production from Acrolein, Methyl Mercaptan and HCN
This report presents the economics of DL-Methionine production from acrolein, methyl mercaptan, and hydrogen cyanide (HCN) in the United States. In this process, refined acrolein and methyl mercaptan are reacted to form MMP (also called methional), which is further reacted with HCN to generate DL-Methionine via a typical carbonate process.
Details: 150 kta United States-based plant | Q3 2024 | 107 pages | Issue D | From $1,199 USD
Could Not Find the Report You Need?
Obtain a Bespoke Report
Get a report targeting the process in which you are interested
See Offer Details
Understand Bespoke Reports and how you can easily order them
Check Editions & Pricing
Complete a brief form and see a quotation for your Bespoke Report
Other Related Production Cost Reports

Hydrogen Cyanide from Ammonia and Natural Gas (Without Air)
This report provides the economics of Hydrogen Cyanide production in the United States using a direct synthesis method similar to BMA (Blausäure-Methan-Ammoniak) process, which involves the reaction of ammonia and methane (natural gas) without air.
Details: 60 kta United States-based plant | Q3 2024 | 107 pages | Issue B | From $799 USD

Methyl Mercaptan from Natural Gas, Sulfur and Methanol (H2 Intermediate)
This study presents the economics of Methyl Mercaptan production from natural gas, sulfur, and methanol in the USA. In this process, hydrogen is produced from natural gas then reacted with sulfur to obtain hydrogen sulfide. Subsequently, hydrogen sulfide and methanol are reacted to produce Methyl Mercaptan.
Details: 50 kta United States-based plant | Q3 2024 | 107 pages | Issue C | From $1,499 USD

Hydrogen Cyanide from Ammonia and Natural Gas (With Air)
This study provides the economics of Hydrogen Cyanide production in the United States using a direct synthesis method similar to Andrussow process, which involves the reaction of ammonia, methane (natural gas), and air to produce HCN.
Details: 100 kta United States-based plant | Q3 2024 | 107 pages | Issue A | From $799 USD

Acrolein Production
This report presents the economics of Acrolein production from propylene in the United States, via catalytic oxidation.
Details: 30 kta United States-based plant | Q3 2024 | 107 pages | Issue A | From $799 USD

Methyl Mercaptan from Natural Gas, Methanol and Sulfur (Carbon Disulfide Co-Product)
This study presents the economics of Methyl Mercaptan production from natural gas, methanol and sulfur in the USA. In this process, sulfur and natural gas are reacted to produce hydrogen sulfide and carbon disulfide. Subsequently, hydrogen sulfide and methanol are reacted to produce Methyl Mercaptan.
Details: 50 kta United States-based plant | Q3 2024 | 107 pages | Issue A | From $5,500 USD
+800 Reports Developed, Targeting +250 Commodities
Vast Report Library
858 independent and up-to-date reports examining embryonic and established production processes.
Free Sample Reports
Quickly understand the structure and depth of content of our professional reports.