Commodity Production Costs Report
L-Lysine-HCl Production from Glucose
Lysine Operating Costs & Plant Construction Costs
This feasibility study approaches an economic analysis of L-Lysine Monohydrochloride (or L-Lysine-HCl) production from glucose syrup in the United States using a conventional fermentation process. The L-Lysine-HCl is recovered via ion-exchange absorption and crystallization.
The report provides a comprehensive study of Lysine production and related Lysine production cost, covering three key aspects: a complete description of the Lysine production process examined; an in-depth analysis of the related Lysine plant capital cost (Capex); and an evaluation of the respective Lysine plant operating costs (Opex).
The Lysine production process description includes a block flow diagram (BFD), an overview of the industrial site installations, detailing both the process unit and the necessary infrastructure, process consumption figures and comprehensive process flow diagrams (PFD). The Lysine plant capital cost analysis breaks down the Capex by plant cost (i.e., ISBL, OSBL and Contingency); owner's cost; working capital; and costs incurred during industrial plant commissioning and start-up. The Lysine plant operating costs analysis covers operating expenses, including variable costs like raw materials and utilities, and fixed costs such as maintenance, labor, and depreciation.
Key reference(s): ?
The process under analysis comprises three major sections: (1) fermentation; (2) product recovery; and (3) product concentration, drying and packaging.
Fermentation. The culture media used in fermentation is prepared by mixing process water, glucose and nutrients. The fermentation is performed in fed-batch mode and under aerobic conditions. At the batch phase, the microorganism seed is fed into the fermenters, which were previously filled with the fermentation batch medium. After glucose exhaustion, the batch phase is finished and the fed-batch phase is started, during which, glucose and nutrients are continuously supplied until the desired L-Lysine concentration is achieved. At the end of the fermentation, the broth is sent to a buffer tank to provide a continuous flow in the further process steps.
Product recovery. The fermentation broth is sent to an ultrafiltration system for the removal of cell debris and other suspended solids. Subsequently, the liquor from ultrafiltration is fed to ion exchange columns, where L-Lysine is selectively adsorbed. The L-Lysine adsorbed is eluted from the ion exchange resins by washing with an aqueous ammonia solution.
Product concentration, drying and packaging. The L-Lysine eluate from ion exchange columns is mixed with mother liquor from product filtration and concentrated by evaporation. The concentrated lysine solution is acidified with hydrochloric acid, and free L-Lysine is converted to L-Lysine-HCl. Subsequently, the L-Lysine-HCl solution is sent to the crystallizer, and lysine salt is filtered. The mother liquor is recycled to the evaporator and the wet cake is conveyed to dryers. Final dry L-Lysine-HCl (98.5 wt%) is obtained and sent to packaging line before being stored in bags.
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Professional report based on Q3 2024 economic data, ensuring timely evaluations.
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Content Highlights
Plant Capital Cost Summary
Summary outlining the capital cost required for building the Lysine production plant examined.
Plant Capital Cost Details
Detailing of fixed capital (ISBL, OSBL & Owner’s Cost), working capital and additional capital requirements.
Plant Cost Breakdowns
Breakdown of Lysine process unit (ISBL) costs and infrastructure (OSBL) costs; plant cost breakdown per discipline.
Operating Costs Summary
Summary presenting the operating variable costs and the total operating cost of the Lysine production plant studied.
Operating Cost Details
Detailing of utilities costs, operating fixed costs and depreciation.
Plant Capacity Assessment
Comparative analysis of capital investment and operating costs for different Lysine plant capacities.
Production Process Information
Block Flow Diagram, descriptions of process unit (ISBL) and site infrastructure (OSBL).
Process Consumptions
Raw materials and utilities consumption figures, by-products credits, labor requirements
Process Diagrams
Process flow diagrams (PFD), equipment list and industrial site configuration
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Other Lysine Production Cost Reports
L-Lysine-HCl Production from Raw Sugar
This report presents the economics of Lysine production from raw sugar (sucrose). Sucrose is initially hydrolyzed into glucose and fructose (invert sugar). The invert sugars are then fermented to produce L-Lysine, which is recovered as L-Lysine-HCl. The economic analysis provided assumes a plant located in Germany.
Details: 100 kta Germany-based plant | Q3 2024 | 107 pages | Issue B | From $799 USD
L-Lysine Sulfate Production from Glucose
This report approaches the economics of L-Lysine Sulfate production from glucose syrup. In the process examined, glucose syrup is submitted to fed-batch fermentation to produce L-Lysine. The economic analysis provided assumes a plant located in the United States.
Details: 100 kta United States-based plant | Q3 2024 | 107 pages | Issue C | From $799 USD
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