Lysine Manufacture Technology Description

Online Lysine Data: Manufacture, Uses and Applications

Intratec Chemical Process Library is the first free online encyclopedia of chemical process technologies. Our Library covers not only processes description themselves, but also the economics surrounding chemicals production, providing real-world knowledge on the production of several chemical commodities. Click here to check all chemicals covered.

In this page you will find free data about Lysine, including:

  • What is Lysine
  • How to make Lysine
  • Lysine uses and applications

This page presents brief synopsis of Lysine production technology, describing, in a concise way, relevant technical and economic aspects. Each manufacturing process description will consist of:

  • Major process steps
  • Simplified, schematic flow diagram & key equipment
  • Important safety or environmental considerations
  • Economic perspective, comprising capital expenditures and/or operating expenses

All content from Intratec's Chemical Process Library was produced based on reports published by Intratec. To learn more about Lysine production processes presented below and others examined in Intratec reports, click here.

L-Lysine HCl Manufacture from Glucose

Amino acids are the basis for all proteins and are considered building blocks of life. Among them, lysine (biologically active in its L-stereoisomer form) is one of the essential amino acids not synthesized biologically in the body. In this context, lysine is typically used as a supplement in human food and animal feed.

L-lysine is commonly commercially produced as L-lysine monohydrochloride (L-lysine HCl), with purity higher than 98.5 wt.%, which corresponds to 78.8 wt.% of free lysine.

Technology Description

L-Lysine HCl Manufacture from Glucose - Process Flow Diagram

The following paragraphs, along with the above simplified process diagram, describe a conventional fermentation process for L-lysine HCl production. The process can be divided into three main parts: fermentation; product recovery; and product concentration, drying and packaging.

Product Recovery

The fermentation broth is sent to ...

Product Concentration, Drying and Packaging

The L-lysine eluted from the ion-exchange columns is mixed with ...


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This synopsis is based on the report L-Lysine-HCl Production from Glucose - Cost Analysis. (For more information, click here).