Adipic Acid Manufacture Technology Description

Online Adipic Acid Data: Manufacture, Uses and Applications

Intratec Chemical Process Library is the first free online encyclopedia of chemical process technologies. Our Library covers not only processes description themselves, but also the economics surrounding chemicals production, providing real-world knowledge on the production of several chemical commodities. Click here to check all chemicals covered.

In this page you will find free data about Adipic Acid, including:

  • What is Adipic Acid
  • How to make Adipic Acid
  • Adipic Acid uses and applications

This page presents brief synopsis of Adipic Acid production technology, describing, in a concise way, relevant technical and economic aspects. Each manufacturing process description will consist of:

  • Major process steps
  • Simplified, schematic flow diagram & key equipment
  • Important safety or environmental considerations
  • Economic perspective, comprising capital expenditures and/or operating expenses

Bio-Based Adipic Acid Manufacture

Adipic acid is a dicarboxylic acid that is widely applied to the production of nylon, polyurethanes, plasticizers and other polymers. Its main use is as one of the raw materials for the manufacture of the polyamide nylon 6,6. In 2012, 80% of the total adipic-acid demand was directed to this application.

The traditional production method for adipic acid is based on the oxidation of cyclohexane, a petroleum-based feedstock. However, adipic acid is among the growing group of industrial compounds for which more-sustainable production methods have been developed. A bio-based route to adipic acid has emerged as an alternative to petroleum-derived adipic acid. Bio-adipic acid can be produced from renewable feedstocks, such as sugar and plant-based oils.

Technology Description

Adipic acid is produced by a microorganism-based fermentation process that uses a sucrose solution as the feedstock. The process described below was compiled based on information available in the published literature.

Bio-Based Adipic Acid Technology - Process Flow Diagram

Sugar Inversion

Sucrose is hydrolyzed to fructose and glucose, which are the compounds actually consumed in fermentation. The reaction occurs in an acidic medium, obtained by adding HCl. After inversion, the pH is adjusted with Na2CO3, and the resulting stream is cooled before being sent to the fermentation stage.


The sugars are converted to adipic acid through an aerobic fermentation. The microorganism culture is ...

Cell Separation

The fermentation broth is ...

Product Recovery

The solution is sent to the concentration column, where ...

To access a report with more content about this process click here.