Production Cost Report
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Methionine
Methionine
Bio-Methionine
Methionine (a.k.a. Bio-Methionine) is an essential amino acid that is not synthesized by animals, so it must be obtained from their diets. With an asymmetric carbon, Methionine molecules can be D (Dextrogyre) or L (Levogyre), optical isomers. While the L-Methionine is the biologically active form of Methionine in proteins, the D-Methionine is actually converted into L-Methionine by enzymatic processes inside animal bodies in such a way that L-and D-Methionine are equivalent for animal nutrition. Methionine is traditionally available as: D,L-Methionine (DLM) and Methionine Hydroxy Analog (MHA).
The uses and applications of Methionine may vary according to its specification. The main forms of Methionine are D,L-Methionine powder (DLM, 99% active substance); D,L-Methionine solution (DLM, 40% purity); L-Methionine powder; Methionine Hydroxy Analogue free acid liquid (MHA, 88% active substance); and Methionine Hydroxy Analogue calcium salt powder (MHA, 84% purity).

Methionine Cost of Production | Q4 2023

Updated Reports Examining Methionine Manufacturing Costs

Intratec offers professional, easy-to-understand Commodity Cost of Production reports analyzing the costs of Methionine manufacturing processes. Each report describes an industrial plant based on a specific Methionine process. The report also presents an independent analysis of the costs of Methionine production, encompassing plant capital costs (capex) and plant operating costs (opex). All reports are based on the most recent economic data available (Q4 2023).

DL-Methionine from Methional and Hydrogen Cyanide

This report provides the economics of DL-Methionine production from methional and hydrogen cyanide (HCN) in the United States via a typical carbonate process. Initially, methional is reacted with HCN, ammonia and carbon dioxide to produce 5-(2-methylmercaptoethyl)-hydantoin (MMEH), which is hydrolyzed to potassium methioninate (KMET). Finally, the KMET is acidified, liberating methionine.

Details: 150 kta United States-based plant   |   Q4 2023   |   108 pages   From $799 USD

The cost analyses presented in the report Methionine E11A target a 150 kta (kilometric tons per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Bio-Methionine Production from Raw Sugar

This report presents the economics of L-Methionine production from raw sugar (sucrose) in Germany using a process similar to the technology developed by Metabolic Explorer. In this process, sucrose is diluted and sucrose is hydrolyzed into glucose and fructose (invert sugars). The invert sugars are then fermented in an aerobic environment to produce L-Methionine.

Details: 80 kta Germany-based plant   |   Q4 2023   |   109 pages   From $799 USD

The cost analyses presented in the report Methionine E21B target a 80 kta (kilometric tons per annum) Germany-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Bio-Methionine Production from Glucose

This report presents the economics of L-Methionine production from glucose syrup in the United States using a process similar to the technology developed by Metabolic Explorer. In this process, glucose is fermented in an aerobic environment to produce L-Methionine.

Details: 80 kta United States-based plant   |   Q4 2023   |   109 pages   From $799 USD

The cost analyses presented in the report Methionine E31A target a 80 kta (kilometric tons per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

DL-Methionine Production from Acrolein, Methyl Mercaptan and HCN

This report presents the economics of DL-Methionine production from acrolein, methyl mercaptan, and hydrogen cyanide (HCN) in the United States. In this process, refined acrolein and methyl mercaptan are reacted to form MMP (also called methional), which is further reacted with HCN to generate DL-Methionine via a typical carbonate process.

Details: 150 kta United States-based plant   |   Q4 2023   |   109 pages   From $1,199 USD

The cost analyses presented in the report Methionine E41A target a 150 kta (kilometric tons per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Methionine Hydroxy Analog Production from Methional and HCN

This report presents the economics of Methionine Hydroxy Analog production from methional and hydrogen cyanide (HCN) in the United States via a typical process. In this process, methional reacts with HCN to produce hydroxy methylthiobutyronitrile (HMBN) intermediate, which is hydrolyzed to Methionine Hydroxy Analog.

Details: 150 kta United States-based plant   |   Q4 2023   |   107 pages   From $799 USD

The cost analyses presented in the report Methionine E51A target a 150 kta (kilometric tons per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Methionine Hydroxy Analog from Acrolein, Methyl Mercaptan and HCN

This study presents the economics of Methionine Hydroxy Analog production from acrolein, methyl mercaptan, and hydrogen cyanide (HCN) in the United States. In this process, acrolein and methyl mercaptan are reacted to form methional. The methional reacts with HCN to produce hydroxy methylthiobutyronitrile (HMBN) intermediate, which is hydrolyzed to Methionine Hydroxy Analog.

Details: 150 kta United States-based plant   |   Q4 2023   |   109 pages   From $1,199 USD

The cost analyses presented in the report Methionine E61A target a 150 kta (kilometric tons per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

DL-Methionine from Propylene, Methyl Mercaptan and HCN

This study presents the economics of an integrated process for DL-Methionine production starting from propylene in the USA. Initially, propylene is oxidized to acrolein, which is then reacted with methyl mercaptan to generate methional. Finally, methional is reacted with hydrogen cyanide (HCN) to form methionine via a typical carbonate process.

Details: 150 kta United States-based plant   |   Q4 2023   |   109 pages   From $1,499 USD

The cost analyses presented in the report Methionine E71A target a 150 kta (kilometric tons per annum) United States-based plant. For those interested in cost analyses considering other plant capacities and/or locations, Intratec offers a customized analysis as an optional feature.

Could Not Find the Production Cost Report you Need?

If none of the Methionine reports listed above fits your needs, you can request a bespoke report examining the process you are interested in! You will have a report tailored to your needs, in which you defined production process, industrial plant capacity and location!

Details: Customer-defined Plant Location & Capacity  |   Q4 2023 From $2,900 USD

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About Methionine. Methionine (a.k.a. Bio-Methionine) is an essential amino acid that is not synthesized by animals, so it must be obtained from their diets. With an asymmetric carbon, Methionine molecules can be D (Dextrogyre) or L (Levogyre), optical isomers. While the L-Methionine is the biologically active form of Methionine in proteins, the D-Methionine is actually converted into L-Methionine by enzymatic processes inside animal bodies in such a way that L-and D-Methionine are equivalent for animal nutrition. Methionine is traditionally available as: D,L-Methionine (DLM) and Methionine Hydroxy Analog (MHA).

Methionine Uses. The uses and applications of Methionine may vary according to its specification. The main forms of Methionine are D,L-Methionine powder (DLM,99% active substance); D,L-Methionine solution (DLM,40% purity); L-Methionine powder; Methionine Hydroxy Analogue free acid liquid (MHA,88% active substance); and Methionine Hydroxy Analogue calcium salt powder (MHA,84% purity).

Intratec Methodology. Intratec distilled its expertise, gained from more than a decade of supporting companies worldwide in the analysis of commodities markets and process economics, and developed a consistent report development methodology.

The methodology ensures a holistic, coherent, and consistent techno-economic evaluation, guiding the development of a report that allows readers to fully understand a specific process technology for the production of a commodity. In addition to being based on a common methodology, all Intratec reports that approach industrial processes have a common structure, i.e., indexes, tables and charts share similar standards. This ensures that Intratec’s readers know upfront what they will get and, more than that, will be able to compare technologies addressed in different reports.

Our methodology is continuously tested and proven by the many corporations involved with the commodities sector, R&D centers, EPC companies, financial institutions and government agencies that rely on our reports.

Check Intratec Methodology to better understand how Intratec develops Commodity Cost of Production Reports.